The growing size of the U.S. debt, and the concerns over how much more it will increase, is very much on the minds of investors, markets and lawmakers. The developments were tied in part to Moody’s announcement that it was downgrading the U.S. credit rating over concerns about large annual deficits, debt and rising interest costs. Amna Nawaz discussed more with David Wessel.

The Israeli military allowed humanitarian aid into Gaza for the first time in more than 11 weeks. It came after Britain, France and Canada threatened to sanction Israel if it did not provide assistance. Israel also ordered Gaza’s second-largest city evacuated, part of a new ground operation that Israel says will not only clear Hamas, but also hold “all of the Gaza Strip.” Nick Schifrin reports.

In our news wrap Monday, the Supreme Court allowed the Trump administration to strip legal protections from hundreds of thousands of Venezuelan immigrants, President Trump says Russia and Ukraine will begin ceasefire negotiations, the head of CBS News announced her resignation and the FAA is investigating a two-second outage involving the facility that handles air traffic at Newark airport.

Former President Biden has been diagnosed with an aggressive form of prostate cancer. Among men in the U.S., prostate cancer is the most common cancer and the second leading cause of cancer deaths. Geoff Bennett spoke with Dr. Jay Raman, chair of the Department of Urology at Penn State Health.

It was 45 years ago today when Mount St. Helens erupted, triggering the biggest landslide in Earth’s recorded history and creating an ash cloud that reached across the country. John Yang looks back at the deadliest and most destructive volcanic eruption in U.S. history with Steve Olson, author of “Eruption: The Untold Story of Mount St. Helens.”

In late April, the Trump administration told hundreds of scientists and experts that they were no longer needed to compile the next national climate assessment, a flagship report mandated by Congress to catalog the ways climate change affects the country. John Yang speaks with Elizabeth Koebele, an associate professor at the University of Nevada, Reno, who was among the recipients of that message.

On Monday, President Trump is expected to sign the bipartisan Take It Down Act, which calls for stricter penalties for posting sexually explicit images online without the subject’s consent or with harmful intent — what’s called “revenge porn.” Ali Rogin speaks with tech journalist Laurie Segall, CEO of Mostly Human Media, to learn more.

Treasury Secretary Bessent seemed to acknowledge Sunday that President Trump’s tariffs may lead to some prices going up, but downplayed fears that it would fuel inflation. This past week, a closely watched measure of consumer sentiment slid to a near-record low, largely on concerns about trade policy. Personal finance expert Erin Lowry joins Ali Rogin to discuss.

In our news wrap Sunday, former President Biden has been diagnosed with an aggressive form of prostate cancer, Pope Leo XIV delivered his inaugural Mass at St. Peter’s Square, Israel’s military said it began extensive ground operations in Gaza, and the FBI identified the person responsible for an explosion at a California fertility clinic.

This week marked the 40th anniversary of one of the worst tragedies in Philadelphia’s history. In May 1985, the city’s police department dropped an improvised bomb on a residential home that housed the Black revolutionary organization MOVE. The bomb and ensuing fire killed 11 people, including five children, and destroyed more than 60 nearby homes. Ali Rogin reports.

The Trump administration's feud with major American universities escalated this week as a federal antisemitism task force notified Harvard that $450 million of the school’s research grants are being cut. That’s on top of the $2.2 billion it had previously frozen. Laura Barrón-López spoke with one of the affected researchers, Joan Brugge, director of Harvard’s Ludwig Cancer Center.

The Hmong are an ethnic group living primarily in China and Southeast Asia. There are communities of Hmong migrants across the globe. For Asian American and Pacific Islander Heritage Month, Isabella Jibilian of Rhode Island PBS Weekly spoke with a Hmong family about their history and their journey to America.

In our news wrap Saturday, severe storms in the Midwest and South left nearly two dozen people dead, the Supreme Court said the Trump administration cannot deport a group of Venezuelans detained in Texas using the Alien Enemies Act, Trump plans to have separate calls with Putin and Zelenskyy on Monday, and World Pride festivities kicked off in Washington, D.C.

Israel is mobilizing forces for a new ground assault in Gaza, after Palestinian officials said about 300 people died in waves of airstrikes over the past 72 hours. Israeli officials say the objective is to pressure Hamas into freeing the remaining hostages held in Gaza. Meanwhile, ceasefire talks resumed Saturday in Qatar. John Yang speaks with The Washington Post’s Gerry Shih for more.

In highly anticipated peace talks, Russian and Ukrainian officials agreed to exchange 1,000 prisoners, the war’s largest swap. While they agreed to keep talking, there was no breakthrough for peace and the two sides seemed even further apart. Nick Schifrin reports and Amna Nawaz speaks with former State Department official Andrew Weiss for perspective on the state of negotiations.

In our news wrap Friday, Israeli Defense Forces struck two Houthi-controlled ports in Yemen and launched dozens of airstrikes across Gaza, a transit strike in New Jersey forced 350,000 people to make alternative plans, group of GOP lawmakers blocked President Trump's "big, beautiful bill" and New Orleans police say ten inmates who escaped from jail may have had help from the inside.

This week, President Trump visited three Middle Eastern nations where his family has deep business ties. Over the past month, billions of dollars have poured into Trump-owned companies. It has revived longstanding questions about whether the financial windfalls are influencing policy. White House correspondent Laura Barrón-López reports.

Doctors announced this week that they have treated a newborn baby with a rare genetic disease using the world’s first personalized gene editing therapy. Geoff Bennett discussed the treatment and its potential with Dr. Peter Marks. He oversaw gene therapy treatment and vaccine safety and approval for the FDA before he left in March.

New York Times columnist David Brooks and Washington Post associate editor Jonathan Capehart join Amna Nawaz to discuss the week in politics, including President Trump's trip to the Middle East and his policy shifts in the region, Qatar’s luxury plane gift, the Supreme Court's birthright citizenship hearing, talks of an immigration reality show and the administration investigating James Comey.

He’s a writer who mines his own history to look deeply at broader currents of working-class American life. In his new novel, Ocean Vuong crafts a narrative that weaves together themes of grief, healing and resilience. Senior Arts Correspondent Jeffrey Brown sat down with Vuong to discuss "The Emperor of Gladness" for our arts and culture series, CANVAS.