Lebanon's economy and food security are at a breaking point, and calls for change have been years in the making. The same factions have ruled Lebanon for decades, and many accuse them of benefiting from corruption while ordinary people starve. Lebanon's Former Deputy Prime Minister Ghassan Hasbani joins the program to discuss.

Mona Fawaz is Professor of Urban Studies at the American University of Beirut and an active critic of the government in Lebanon. She and her family were in Beirut at the time of Tuesday's explosion. She joins Christiane to discuss her experience and assess the government's response to the situation.

Remember the name Theranos? It was touted as a revolutionary blood-testing start-up--until 2018, when it came crashing down and its founder, Elizabeth Holmes, was charged with fraud. Tyler Shultz worked at the company before becoming a whistleblower about the technology, which didn't actually work. He joins Hari to discuss lessons learned as it relates to the hunt for a COVID-19 vaccine.

A suit filed in Washington, D.C. raises stunning new allegations against Saudi Crown Prince Mohammad Bin Salman. Dr. Saad Al-Jabri, a former top Saudi intelligence official, claims Bin Salman sent an assassination squad to kill him just two weeks after the brutal murder of journalist Jamal Khashoggi. His son joins Christiane from Toronto for this exclusive interview.

New York Times Investigative Correspondent Mark Mazzetti is running down the latest allegations against the Saudi leadership, as well as new reports that Saudi Arabia may be moving toward developing a nuclear weapon. He joins Christiane from Washington to discuss.

In his new book, political strategist Stuart Stevens turns on his old party. Titled "It Was All a Lie: How the Republican Party Became Donald Trump," the book argues President Trump is the natural outcome of five decades of Republican hypocrisy and self-delusion.

What's at stake for voters when a president and his party drum up fears about an election's integrity? LaTosha Brown is a community organizer, political strategist and co-founder of the Black Voters Matter Fund, and Ari Berman is an author and senior reporter at Mother Jones. They tell Hari Sreenivasan what voters must watch out for this fall.

Christiane speaks with one of the few remaining survivors of Hiroshima: 88-year-old Setsuko Thurlow, who became an activist after surviving the bombing and received the Nobel Peace Prize on behalf of the international campaign to abolish nuclear weapons in 2017. She recounts the agonizing memories and explains why there is reason for hope.

This year, a historic British Vogue September issue highlights activists in the fight for racial justice. The cover was the work of Misan Harriman, the first Black photographer to shoot a September cover, backed by an all-Black team. The cover features soccer star and anti-poverty campaigner Marcus Rashford and model and mental-health activist Adwoa Aboah. Harriman tells Christiane about his work.

Oprah Winfrey says Isabel Wilkerson's book "Caste: The Origins of Our Discontents" is a game-changer and the most important volume she's ever chosen for her book club. Wilkerson was the first Black woman to win the Pulitzer Prize for journalism. Her latest book calls out America's obsession with the term "race."

Global pandemic notwithstanding, President Trump has launched an on-again-off-again verbal war against America's leading infectious disease expert: his task force adviser, Dr. Anthony Fauci. The president recently tweeted that Fauci was "wrong" that the surge in cases is due to the country's failure to shut down properly. Fauci joins Walter Isaacson to discuss the challenges facing the U.S.

Poll after poll shows President Trump's support in steady decline, with many voters citing the pandemic response and racial equality as key election issues. Will the campaign change its strategy? Joining Christiane from Virginia to answer that question is Steve Cortes, a Trump 2020 senior adviser.

Lebanon - one of the worst hit Middle East countries from coronavirus, and teetering on the brink of economic collapse, has now been hit by a massive explosion in the capital of Beirut. Local authorities are warning that many are injured and buildings across the city have been damaged. CNN reporter Ben Wedeman was standing by on the ground for this special report.

In Mississippi, which is on track to be the top state for coronavirus infection, the school district in the city of Corinth re-opened its doors last week. Dr. Edward Lee Childress is Superintendent in Corinth. After reopening schools in his district, positive cases of COVID-19 emerged immediately. He speaks to Christiane about how his district is managing.

Megan Rapinoe is a global soccer icon: an Olympic gold medalist, Women's World Cup champion and FIFA Women's Player of 2019. She's also a role model for thoughtful political activism in sports. Now, she joins the ranks of talk show hosts, with her new HBO series "Seeing America with Megan Rapinoe," the next phase in her personal campaign for women's rights and racial justice.

Dr. Francis Collins has led public health research in the United States for 20 years. As Director of the National Institutes of Health, he is the supervisor of Dr. Anthony Fauci, the nation's top expert on infectious disease. Collins joins Walter Isaacson to offer perspective on current vaccine trials, and to discuss how his faith sustains him during this pandemic.

Arne Duncan was Secretary of Education under Barack Obama. He says the lack of leadership from Washington, and a proper national coordination plan on schools, is proving to be devastating and that the United States is failing its students.

Amid the Black Lives Matter protests, many industries have been experiencing long overdue reckonings with racism. The fashion industry is no exception. Three years ago, British Vogue elevated Edward Enninful to editor-in-chief--making Enninful the first Black gay man to hold the position. He joins Christiane to discuss his mission to strengthen diversity and inclusion at the publication.

Award-winning author James McBride has built a career exploring American culture and identity through storytelling. His latest book "Deacon King Kong" looks at how communities pull together in the face of violence and trauma. He joins Michel Martin to discuss the work.

Who is the man in the Oval Office, really? Mary Trump is President Trump's niece and a clinical psychologist. Her new memoir "Too Much and Never Enough" abandons family loyalty and the code of silence to provide a revealing portrait of her uncle. She joins Christiane to discuss.