Just months ahead of a national election, Nicaraguan President Daniel Ortega regime has imprisoned seven opposition leaders. Human rights defender Bianca Jagger is one of Nicaragua’s best-known pro-democracy advocates and joins the show to explain what’s going on.

Bill Bratton knows the knotty issues around police reform inside and out: As former police chief in Boston, New York and Los Angeles, Bratton won accolades for a historic decline in crime rates on his beat. His new book is called "The Profession: A Memoir of Community, Race, and the Arc of Policing in America." He joins the show from New York.

Today, President Biden and U.K. Prime Minister Boris Johnson co-signed a new Atlantic Charter: The foundational document of the "special relationship" between the U.K. and the U.S., but it is no guarantee of a warm relationship between the two leaders. To assess the Biden-Johnson working relationship, Bianna speaks with Tom McTague of The Atlantic and Mark Landler of The New York Times.

Moderna chairman Noubar Afeyan has co-authored a report as the CEO of Flagship Pioneering, along with the Eurasia Group, on lessons learned from the Covid crisis and how to build a better future.

The meeting comes just a few days after Mexico’s huge midterm elections, the most polarized in years with a shocking level of violence: at least 96 politicians and candidates were killed during the campaign.

With new strains of COVID-19 emerging across the globe, Richard Hatchett argues the only way to win the pandemic battle is to create a variant-proof world.

Senator Kirsten Gillibrand of New York is hoping to overhaul the way the military responds to sexual assault cases, and this time she has the backing of the president and numerous colleagues who voted against it last time it came to the floor.

The LA Times Billionaire Owner Dr. Patrick Soon-Shiong talks growing up in South Africa to Chinese immigrants during Apartheid.

As President Biden lands in Europe for a week of summits, he sets himself a high bar. In his meetings with G7 and NATO leaders and in his face-to-face with Vladimir Putin, Biden is out to prove the viability of democratic institutions and alliances.

Chris Krebs served as the director of the US Cybersecurity and Infrastructure Security Agency and joins the show from Washington.

When companies’ data are held hostage and they are presented with a demand for payment, should they just go ahead and pay? The U.S. government urges them not to, but many victims see payment as the quickest – and sometimes cheapest – solution. Kurtis Minder is a ransomware negotiator and joins the show to explain why this is.

Naomi Osaka's decision to pull out of the French Open, rather than face the tournament’s press conferences, is triggering a conversation about the relationship between athletes and the media.

Vice President Kamala Harris met with Guatemala’s president, as well as community leaders, to discuss the issues forcing people to flee their homes – like violence, corruption, climate, and poverty.

Ben Rhondes makes the case that the US bears a significant responsibility for the current anemic state of global liberal democracy. He joins the show to explain his thesis.

Paxton Smith tossed out her approved speech, took out a new piece of paper from under her gown, and went on to address the state’s new abortion bill, which prohibits most abortions when a fetal heartbeat is detected as early as 6 weeks – with no exceptions for rape or incest.

Dr. Ezekiel Emanuel joins the show.

Linda Thomas-Greenfield joins the show.

Wu’er Kaixi and Finn Lau join the show.

Esther Duflo and Abhijit Banerjee are Nobel Prize-winning economists and warn that India’s COVID problem is now the world’s problem.

Matt Hancock is the U.K.’s Secretary of State for Health and Social Care, and joins the show to discuss COVID-19 and a more equitable vaccine rollout.