Mack Beggs was a star wrestler at his Texas high school. Although he was a transgender boy, he was told he had to compete on the girls’ team. Mack’s story is one of several featured in the Hulu documentary “Changing the Game.” Beggs joins the show alongside his grandmother Nancy to speak with Hari Sreenivasan about his experiences and the recent wave of anti-trans legislation in the United States.

President Biden has arrived in Geneva prior to his first meeting with Russian President Vladimir Putin tomorrow. The agenda certainly will include Iran. This week’s presidential election in Iran is widely expected to put an anti-western hard-liner in power: cleric and judiciary chief Ebrahim Raisi. To discuss what this would mean for Iran, Christiane speaks with expert Abbas Milani.

50 years ago in Berkeley, California, chef Alice Waters opened Chez Panisse and launched the farm-to-table movement in the West. Her latest book makes the case for “slow food.” She joins the show from California to discuss.

Four-time Grammy-winning singer Angélique Kidjo has just released a new album, “Mother Nature,” which is an ode to the African continent and its cultures. Kidjo shares her spotlight with a new generation of African musical artists, including Burna Boy, Sampa the Great and Mr Eazi. Kidjo joins the show to talk about making music with a message that you can dance to.

A country music legend, singer and songwriter Willie Nelson has made two new albums in the past year and has taken part in multiple concerts, benefits and PSAs. His new bestseller, "Letters to America," offers up a dose of advice and hope.

The NATO summit communiqué calls Russia a "threat" and highlights China's military ambitions for the first time -- describing Beijing as presenting "challenges." Joining the show to discuss all this is NATO Secretary-General Jens Stoltenberg, who met Biden in Brussels today.

Israel's former Foreign Minister and peace negotiator Tzipi Livni joined Christiane from Tel Aviv to discuss the complex challenges facing the fragile new government in Israel.

Pulitzer prize-winning ProPublica reporter Jesse Eisinger speaks to our Hari Sreenivasan about how the world’s richest men -- Jeff Bezos, Elon Musk, Rupert Murdoch to name a few, legally work the system to avoid paying more than a fraction of their earnings in tax.

At the first G7 meeting in two years, leaders of the world's largest economies look to present a unified front against authoritarian aggression. Senior Director for Europe on the US National Security Council Amanda Sloat joins Bianna Golodryga, standing in for Christiane Amanpour, to discuss.

As President Biden gets ready to meet Vladimir Putin in Geneva, Russia has all but liquidated Alexey Navalny’s opposition movement this week. A Moscow court designated the two organisations linked to the Kremlin critic as “extremist” groups, forcing them to shut down-- a charge they deny. Vladimir Ashurkov, the Executive Director of Navalny’s anti-corruption foundation, weighs in.

As more businesses welcome employees back into workspaces, psychology professor and author of ‘iGen’, Jean Twenge explains how to manage the transition.

Jamie Metzl is an adviser to the WHO’s committee on human genome editing and was among the first to argue the virus likely escaped from a lab in Wuhan. Once widely dismissed, the theory is now gaining traction. To unpack it all, Metzl speaks with Hari Sreenivasan.

Just months ahead of a national election, Nicaraguan President Daniel Ortega regime has imprisoned seven opposition leaders. Human rights defender Bianca Jagger is one of Nicaragua’s best-known pro-democracy advocates and joins the show to explain what’s going on.

Bill Bratton knows the knotty issues around police reform inside and out: As former police chief in Boston, New York and Los Angeles, Bratton won accolades for a historic decline in crime rates on his beat. His new book is called "The Profession: A Memoir of Community, Race, and the Arc of Policing in America." He joins the show from New York.

Today, President Biden and U.K. Prime Minister Boris Johnson co-signed a new Atlantic Charter: The foundational document of the "special relationship" between the U.K. and the U.S., but it is no guarantee of a warm relationship between the two leaders. To assess the Biden-Johnson working relationship, Bianna speaks with Tom McTague of The Atlantic and Mark Landler of The New York Times.

Moderna chairman Noubar Afeyan has co-authored a report as the CEO of Flagship Pioneering, along with the Eurasia Group, on lessons learned from the Covid crisis and how to build a better future.

The meeting comes just a few days after Mexico’s huge midterm elections, the most polarized in years with a shocking level of violence: at least 96 politicians and candidates were killed during the campaign.

With new strains of COVID-19 emerging across the globe, Richard Hatchett argues the only way to win the pandemic battle is to create a variant-proof world.

Senator Kirsten Gillibrand of New York is hoping to overhaul the way the military responds to sexual assault cases, and this time she has the backing of the president and numerous colleagues who voted against it last time it came to the floor.

The LA Times Billionaire Owner Dr. Patrick Soon-Shiong talks growing up in South Africa to Chinese immigrants during Apartheid.