Pulitzer Prize-winning journalist Fox Butterfield joins the program to discuss his new book, which explores whether crime is something passed down through families.

As President Trump gets debriefed on the latest from Saudi Arabia, fallout grows over the disappearance of journalist Jamal Khashoggi. New York Times Columnist Thomas Friedman tells Christiane Amanpour about his struggle to square his early support for the Crown Prince with Mohammed Bin Salman’s authoritarian streak.

Alicia Menendez sits down with Amandla Stenberg, star of the new movie “The Hate U Give.”

Former San Antonio Mayor Julian Castro has the resume and the personal story to help leap democrats out of the doldrums. But does his party have a “Latino problem?”

Cindy Shank was imprisoned for fifteen years for her boyfriend’s crimes. She and her brother, filmmaker Rudy Valdez, talk to Hari Sreenivasan about the compulsory sentence that tore their family apart.

As evidence mounts tying the disappearance of Saudi journalist Jamal Khashoggi to the country’s Crown Prince, will Republican Senators stand up for a moral American policy? Senator Ben Sasse joins the program to discuss. His new book wrestles with the anger kicked up by America’s deeply divided political scene.

Two other guests weigh-in: prominent Saudi dissident, scholar Madawi Al-Rasheed says she now feels threatened by the long arm of the regime, and Taha Ozhan was an adviser to the former Turkish Prime Minister and considered Khashoggi a friend.

The disappearance of Saudi journalist Jamal Khashoggi puts the spotlight on reporters who put their lives on the line. Celebrated correspondent Marie Colvin gave her life in Syria, and now the Hollywood actress Rosamund Pike plays her in a new film. She joins the program along with Colvin’s friend and fellow journalist Lindsey Hilsum, who has written a new biography about her life.

Biochemist Jennifer Doudna tells Walter Isaacson about the extraordinary gene-editing technology, CRISPR.

Shocking reports of voter suppression ahead of the U.S. midterms. Carol Anderson, author of “One Person, No Vote,” joins the program to discuss how the rules and technicalities of voting are becoming a partisan tactic to weigh down the opposition, threatening our democracy.

No sign yet of any public explanation as sources say the Kingdom is preparing to admit Jamal Khashoggi’s death was the result of a botched interrogation. CNN International Diplomatic Editor Nic Robertson joins the program from Istanbul.

Actor Paul Dano tries his hand at directing, to great reviews. Dano and his lead actress Carey Mulligan join the program to discuss the new film “Wildlife.”

Princeton Professor Bernard Haykel, who has regular contact with the Saudi Crown Prince, Mohammad Bin Salman, weighs-in on U.S.-Saudi relations and developments on this story.

As international pressure is mounting on Saudi Arabia over the shocking story of Jamal Khashoggi, former Senator Bob Graham joins the program to discuss why the U.S. has placated Saudi Arabia for nearly 20 years.

Alicia Menendez sits down with DeRay Mckesson to discuss his new memoir, “On the Other Side of Freedom: The Case for Hope,” a powerful and personal reflection on racism today.

Christiane Amanpour discusses her show, Amanpour & Company.

Hari Sreenivasan discusses the remarkable new film, “Free Solo,” with its co-director Elizabeth Chai Vasarhelyi and rock climber Alex Honnold.

As midterms loom and the cross-party divide widens, two governors from different sides of the aisle are trying to dial down the toxic rhetoric. Ohio Governor John Kasich and Colorado John Hickenlooper discuss why their message of civility is important, now more than ever.

British actress and Hollywood superstar Keira Knightley joins the program to discuss her latest movie on the revolutionary French writer, “Colette,” and how it strikes a chord with her own advocacy for women’s rights.

The fallout over the mysterious disappearance of Saudi journalist Jamal Khashoggi continues. As all fingers point to Riyadh, author of “Presidents of War” Michael Beschloss joins the program to discuss whether President Trump will turn on a key ally.