South Carolina could possibly break precedent this election year. For the past 17 years, the state has been red through and through, with Republican Senator Lindsey Graham running virtually unchallenged – until now. Jaime Harrison, the first African American Democratic contender for the South Carolina senate seat, joins the program from the state capital.

After years of security cooperation, Israel and the United Arab Emirates have struck an historic peace deal. The move was announced in a joint statement with President Trump, who said it would bring together two of America’s strongest allies in the region. Former Israeli Foreign Minister and veteran peace negotiator Tzipi Livni discusses what this means for the future.

The 26-year-old musician Jacob Collier exploded onto the scene with his 2016 album "In My Room," which was recorded – you guessed it – in his room. He uses multiple tracks and plays most of the music himself, in a recording process that has even extended into his bathroom. On Friday, the Grammy Award winner is releasing his latest album "Djesse Vol. 3," and he joins the show from his home studio.

Sports has been sideswiped by COVID-19. Now, the pandemic looks likely to cancel American college football, as multiple conferences pull their teams for the fall. Sportswriter Dave Zirin and retired NFL defensive end and activist Michael Bennett co-authored the book "Things That Make White People Uncomfortable." They join Hari Sreenivasan to discuss Black Lives Matter and the future of sports.

A core criticism of Harris during the race for the Democratic nomination concerned her career as a prosecutor in California. Having earned a reputation for being tough on crime, she now says that she is determined to combat systemic racial injustice. Activist DeRay Mckesson has spent years drawing attention to institutionalized racism, and he joins the show to discuss Harris' place on the ticket.

Historian Rutger Bregman argues that humans are often so steeped in cynicism that we often miss the truth hiding in plain sight. In his new book "Humankind," Bregman argues that humans are the dominant species not because we are cold, ruthless predators, but because precisely the opposite is true. He joins the program to offer his refreshingly optimistic perspective.

As the pandemic lays bare social, legal, racial and financial injustice in America, it is vital to examine how the system got its start. Kurt Andersen is a best-selling author and journalist whose latest book examines the origins of America’s hyper-capitalism. He speaks with Walter Isaacson about the genesis and propagation of the system--and the need to take a step back.

A historic choice in American presidential politics at a historic time in America: Sen. Kamala Harris becomes the first Black female vice presidential candidate in American history. Valerie Jarrett, former adviser to President Obama, responds to this development.

Upon filing a complaint about vote rigging on Sunday, Belarusian presidential candidate Svetlana Tikhanovskaya was arrested and held for seven hours by authorities. She then fled to neighboring Lithuania, citing concern for the safety of her children. Lithuania’s Foreign Minister played a role in ensuring safe haven for Tikhanovskaya. He joins the program to assess these alarming developments.

The world urgently needs an effective COVID-19 vaccine. Behind much of the research is Bill Gates, who is dedicating billions of dollars to helping ensure that when a vaccine arrives, it will be affordable and accessible to those most in need. He speaks with Walter Isaacson about his belief that much of the testing being done in America is a complete waste.

Andrei Sannikov was once Belarusian President Alexander Lukashenko’s deputy foreign minister, but they are emphatically no longer allies. Sannikov ran against the president in 2010 and came in second, only to be jailed shortly afterwards and subjected to horrifying treatment. He joins the program from Warsaw, Poland, where he is living in exile.

President Trump, still fighting to hide his financial history, now demands that the Manhattan District Attorney reveal why he issued a subpoena for eight years of tax returns and other documents. Trump’s lawyers argue the president is being “harassed.” Christiane speaks with legal analyst Jeffrey Toobin to discuss this as well as Toobin’s new book on the Mueller Investigation.

Beijing’s crackdown on democracy in Hong Kong has re-escalated with the latest high-profile arrest under the new national security law. Claudia Mo spent 30 years as a journalist in the region and now serves as an independent pro-democracy member of the Legislative Council. She joins the show to discuss.

David Kaye served for six years as the United Nations’ Special Rapporteur on the Promotion and Protection of the Right to Freedom of Opinion and Expression, and he joins Hari Sreenivasan to discuss how the pandemic has prompted the newest tactic in the authoritarian leadership playbook.

To discuss the best way forward for the country’s ailing healthcare system, Christiane speaks with progressive Saikat Chakrabarti, who served as chief of staff to Rep. Alexandria Ocasio-Cortez, and Jennifer Granholm, the former governor of Michigan.

Lebanon's economy and food security are at a breaking point, and calls for change have been years in the making. The same factions have ruled Lebanon for decades, and many accuse them of benefiting from corruption while ordinary people starve. Lebanon's Former Deputy Prime Minister Ghassan Hasbani joins the program to discuss.

Mona Fawaz is Professor of Urban Studies at the American University of Beirut and an active critic of the government in Lebanon. She and her family were in Beirut at the time of Tuesday's explosion. She joins Christiane to discuss her experience and assess the government's response to the situation.

Remember the name Theranos? It was touted as a revolutionary blood-testing start-up--until 2018, when it came crashing down and its founder, Elizabeth Holmes, was charged with fraud. Tyler Shultz worked at the company before becoming a whistleblower about the technology, which didn't actually work. He joins Hari to discuss lessons learned as it relates to the hunt for a COVID-19 vaccine.

A suit filed in Washington, D.C. raises stunning new allegations against Saudi Crown Prince Mohammad Bin Salman. Dr. Saad Al-Jabri, a former top Saudi intelligence official, claims Bin Salman sent an assassination squad to kill him just two weeks after the brutal murder of journalist Jamal Khashoggi. His son joins Christiane from Toronto for this exclusive interview.

New York Times Investigative Correspondent Mark Mazzetti is running down the latest allegations against the Saudi leadership, as well as new reports that Saudi Arabia may be moving toward developing a nuclear weapon. He joins Christiane from Washington to discuss.