Antonio Banderas returns to his roots in “Pain and Glory,” a new film directed by – and based on the life of – legendary Spanish filmmaker Pedro Almodóvar. His role is a study on health, ageing and feelings, and is made all the more poignant considering Banderas himself only recently recovered from a heart attack. He joins the program to discuss a role that critics have called his most important.

Award-winning actor John Lithgow is a familiar face on TV, film and stage. He’ll soon be seen portraying former Fox News chairman Roger Ailes in the film “Bombshell.” Before that, he has turned his hand to writing, with a new satirical poetry collection poking fun at the president. He discusses poetical satire with Hari.

Former Secretary of Veterans Affairs David Shulkin is the first former Trump cabinet member to speak completely openly about his experiences. He joins the program to reflect on the greater implications of Alexander Vindman's testimony to House investigators and reveal the inside story of the Trump administration.

In Beirut today, Lebanese Prime Minister Saad Hariri announced his resignation after two weeks of protests triggered by a proposed tax on WhatsApp calls. Mona Fawaz is a professor at the American University of Beirut and has been intimately involved in organizing the protests; she joins the program from Beirut, where demonstrations can still be heard.

Street protests worldwide have now reached Latin America: in Chile, President Sebastián Piñera has replaced his cabinet after days of violent protest and a misguided military crackdown. Meanwhile, Peru, Bolivia, Argentina and Colombia have also seen huge crowds on the streets. Juan Manuel Santos, former president of Colombia and a Nobel Peace Laureate, speaks to Christiane about this unrest.

At age 16, Aarti Shahani was visiting her father in the infamous Rikers Island prison, where he was serving time for a crime she says he was unwittingly involved in. In her new memoir, Shahani comes to terms with the 14 year long legal battle her family faced, and the resentment she felt at being brought to America as a child. She speaks to Michel about how all this shaped her American Dream.

In the wake of the wake of Abu Bakr al-Baghdadi's death, impeachment proceedings in Washington nonetheless continue apace. Joining the program to assess this political battlefield are Republican pollster and strategist Frank Luntz and a congresswoman who sat on the House Judiciary Committee during President Nixon’s impeachment, Elizabeth Holtzman.

ISIS leader Abu Bakr al-Baghdadi was killed in a U.S. raid. A joint U.S.-Kurdish raid reportedly also killed an ISIS spokesman, who might have succeeded the ISIS leader. Now that the leadership has been decapitated, what does it mean for ISIS and the fight against them? Rukmini Callimachi has spent years reporting on the group and Baghdadi’s leadership, and joins the program from Romania.

Basketball player Maya Moore surprised the sports world and her fans when she announced that she would be taking a sabbatical to fight for justice for her friend Jonathan Irons, who is serving a 50-year prison sentence. In 1998, a jury found him guilty of burglary and assault with a deadly weapon, but Moore is certain that Irons is innocent. She joins Michel Martin to share Jonathan's story.

Turkey, Russia and Assad’s Syrian forces have consolidated their influence in Syria while the United States' long time Kurdish allies have been left isolated. Some say that President Trump's actions are motivated by a desire to destroy the legacy of his predecessor, Barack Obama. Former Secretary of State John Kerry speaks to Christiane about policies he helped craft that are now being undone.

Theatre Legend Brian Cox sits down with Christiane Amanpour to discuss Brexit and his work in HBO's "Succession."

Harvard Law Professor Noah Feldman joins Walter to explain why the impeachment fight tests the very limits of the U.S. constitution.

Before #MeToo, there was Anita Hill. Nearly three decades ago, the law professor made the life-changing decision to testify against the confirmation of then-Supreme Court nominee Clarence Thomas, and in doing so, gripped the nation. She sits down with Christiane to discuss harassment, abuse and the politics of today.

”Celestial Bodies” is a book of firsts: it’s the first novel by an Omani woman to be translated into English, and the first work in Arabic to be awarded the prestigious Man Booker International Prize. Author Jokha Alharthi and her co-winner and translator Marilyn Booth speak with Christiane about the book’s breakout success.

Harvard Law Professor Noah Feldman joins Walter Isaacson to discuss the idea of a governing body for Facebook.

Richard Stengel is the former Editor-in-Chief of Time and a former Under Secretary of State in the Obama administration, where he led the department’s counter-disinformation efforts. He joins Walter Isaacson to discuss his new book “Information Wars,” which offers a deep dive into the fake news phenomenon, beginning with his own experience with Ukraine during the Russian invasion of Crimea.

Tom Mueller – no relation to Bob – is a New York Times bestselling author who has spent years studying the complex relationship between whistleblowers and society. His new book is a timely reminder of the challenges and the personal cost to those who dare to tell the truth, and he sits down with Michel to explain how this is ultimately about upholding American values.

U.S. Secretary of Defense Mark Esper is in Saudi Arabia today, amid the deployment of thousands of new U.S. troops to the country to try and visibly confront Iran. Meanwhile, the tumultuous withdrawal of U.S. forces from Syria looks set to benefit Iran’s regional ambitions, as well as Russia’s and the Syrian regime’s. Esper joins Christiane for an exclusive interview in Saudi Arabia.

Rhiannon Giddens is a folk singer and multi-instrumentalist who also happens to be a classically trained opera singer. Having grown up in North Carolina, she’s now on a mission to re-frame the history of African Americans and their contributions to the musical landscape. Giddens sits down with Walter to discuss her latest album, “There Is No Other,” and play a little banjo.

Christiane sits down with Peter Frankopan and Malte Herwig to discuss Peter Handke's controversial Nobel Prize Win. WARNING: This segment contains graphic images.