UK Prime Minister Boris Johnson becomes the first major world leader to be hospitalized for COVID-19. Meanwhile, in the United States, the Surgeon General warns Americans to brace for the “hardest, saddest week ahead, equivalent to Pearl Harbor or 9/11." Physician and author Siddhartha Mukherjee has been studying the progress of the virus. He joins the program to discuss the crisis.

In the early days of the virus’ spread, Iran was hit particularly hard, with more than 60,000 cases and almost 4,000 dead, according to the country’s health ministry. Nonetheless, Iran plans to ease work restrictions soon. Mohammad Nahavandian, the country's Vice President for Economic Affairs, joins the program for an exclusive interview from Tehran.

The legacies of today's leaders will be shaped by their handling of the coronavirus pandemic. But how are they stacking up against the presidents and prime ministers of yesteryear? In a candid conversation with Walter Isaacson, the Pulitzer Prize-winning historian and presidential biographer Jon Meacham dissects the performance of President Trump in this crisis.

Former Republican Governor David Beasley recently contracted COVID-19 but was fortunate enough to fully recover, and has now returned to his job as head of the World Food Programme. He joins the show to describe his own experiences with the virus, and what the WFP is doing to keep its crucial work going in this difficult time.

Some of the strategies individuals can employ to slow the spread of COVID-19 are extremely simple, starting with washing your hands as often as possible. For years, Dr. Atul Gawande has worked with hospitals to lower their infection rates by reminding doctors to do exactly this. A surgeon and "New Yorker" staff writer, Gawande joins the program to reflect on another week of tragedy and challenge.

With many of us staying home, unable to see friends and family in person, it’s a booming time for social media networks like Facebook. But the same question continues to arise: What are these networks doing about misinformation? How do you stop the spread of false and dangerous posts when it comes to a global pandemic with lives at stake? Facebook VP Sir Nick Clegg joins the program to discuss.

Nowhere is the fragility of the U.S. healthcare system more apparent than in America’s poorer communities. Regina Benjamin served as U.S. Surgeon General under President Obama and founded the BayouClinic, serving a poor fishing community in Alabama. Having worked through Hurricane Katrina in 2005, Benjamin talks to Walter about the lessons learned on what to do when disaster strikes rural America.

As the number of COVID-19 infections worldwide climbs to nearly a million, the UK Prime Minister is under fierce criticism for failing to deliver the levels of testing he had promised. To discuss this, Christiane is joined by Tim Spector, the founder of an app designed to track COVID-19 symptoms, alongside NYU infectious disease specialist Dr. Celine Gounder.

The latest figures show that 6.6 million Americans filed claims for unemployment benefits last week. That’s a surge of over 3000% since early March. The pandemic has so far knocked nearly 10 million people out of the country’s workforce. o examine these figures and what it means for the U.S. and world economies, Christiane speaks with former Treasury Secretary Lawrence Summers.

The Bill & Melinda Gates Foundation has been providing both funding and expertise since before the COVID-19 outbreak began, with Bill Gates in particular having sounded the alarm about pandemics for years. Christiane speaks with the CEO of the Foundation to discuss what needs to be done next to fight this outbreak.

Even before the COVID-19 outbreak, many college students struggled to balance school with work and the need to keep a roof over their heads and food on their plates. Now they find themselves in an impossible situation. Sara Goldrick-Rab is perhaps best known for her work combating food and housing insecurity. She tells Hari Sreenivasan what needs to be done for this vulnerable group.

Europe in particular is struggling to find a united approach to combat COVID-19, and one of the countries most in need is Greece -- the EU member nation that was hardest hit by both the 2008 economic crisis and the 2015 migrant crisis. In an exclusive interview, Christiane speaks exclusively with Greece’s Prime Minister about how his country is coping.

Grammy Award-winning musician will.i.am collaborated with Bono, Jennifer Hudson, and Japanese rock star Yoshiki on a new single, “Sing for Life,” inspired by the resilience shown by the world's citizens during this global pandemic. He speaks with Christiane about why he believes that that though we are in self-isolation, we are not alone.

In the U.S., the death toll has surged to more than 4,000, making Tuesday the deadliest day so far in the pandemic, and driving home the desperate need for a better coordinated national response. To discuss the latest, Christiane speaks with the commander of the U.S. Northern Command, Gen. Terrence O’Shaughnessy, who in the worst case scenario would lead the country through the pandemic.

Republican strategist Stuart Stevens has advised key GOP campaigns like Mitt Romney’s 2012 presidential bid. Now he has written a mea culpa for the Washington Post, laying the blame for what he calls President Trump’s failed response to today's pandemic at the feet of all Republicans. He addresses this and discusses his new book, "It Was All a Lie: How the Republican Party Became Donald Trump."

William Burns is a distinguished veteran of the U.S. State Department and joins the program to explain how the crisis could yet present an opportunity to restore democratic leadership.

A new report from the United Nations warns that rates of domestic violence -- particularly against women -- will likely increase now that families are locked down at home. To discuss the good and bad aspects of such enforced closeness, Christiane speaks with sociologist Eric Klinenberg and Dr. Orna Guralnik, psychoanalyst and host of Showtime documentary series “Couples Therapy."

The World Health Organization has said that the best way to tackle this virus is to test, test, test. This is a call to action for pioneering biochemist Dr. Jennifer Doudna and her colleagues at UC Berkeley. They aim to use their biology labs to test up to 2,000 samples per day. Dr. Doudna co-invented the gene editing tool CRISPR, which she hopes will assist her in the battle against COVID-19.

As the battle against coronavirus fills the news, the 2020 presidential race has fallen somewhat to the wayside. The situation appears to be working to President Trump's advantage, with his approval ratings at near historic highs. But will this last until November? Christiane speaks with David Urban, a senior adviser to his re-election effort, about this unprecedented race.

Across the world, the harsh realities of the coronavirus pandemic are setting in. Beth Cameron was the Senior Director for Global Health Security and Biodefense on the White House National Security Council until John Bolton dissolved her office. She is also the author of the now famous, and unused, government pandemic playbook. She joins the show from Washington, D.C.