Well over 200 people have been killed in a brutal crackdown against protestors in Iran, according to Amnesty International, but the Trump administration claims the death toll could be over 1,000. Farnaz Fassihi has been closely documenting these unfolding events for the New York Times, and joins the program to discuss her findings.

Following this week's NATO leaders meeting in London, Hungarian foreign minister Péter Szijjártó responds to President Macron calling NATO "brain dead" and explains Hungary's stance in the international community.

George Church’s current projects range from growing human organs to resurrecting the woolly mammoth. The Harvard genetics professor is at the cutting edge of genetic experimentation, having helped develop the first method for sequencing a genome and the gene editing tool CRISPR. Church joins Walter to discuss this transformative technology and address the ethical issues in genetic engineering.

One week from today, U.K. voters go to the polls in the third major vote in five years. It’s set to be a particularly dramatic general election, with voters having to wrestle with Brexit, something that has completely polarized the country and its parties. Rory Stewart makes the case for why centrism needs to be re-energized and discusses prison sentencing in the U.K.

The latest casualty in the Democratic presidential field was California Senator Kamala Harris, who had initially seemed one to watch, but this week abruptly dropped out of the running. To examine this and the impeachment hearings, Christiane speaks with a bipartisan duo: Democrat Russ Feingold and Republican Mia Love.

In a time of heightened political tension, Jonathan Haidt has a good idea of what’s driving this polarized atmosphere around the world. He is a social psychologist who believes social media has transformed in recent years to become an “outrage machine,” spreading anger and toxicity. He sits down with Hari to discuss this difficult problem and what the possible solutions could be.

Today, four constitutional scholars testified in front of the House Judiciary Committee about impeachment. It follows the testimony to the Intelligence Committee of multiple career foreign service officials, whom critics have said were sidelined by President Trump, leaving key national security issues in the hands of cronies. Michael Lewis, author of “The Fifth Risk," joins the program to discuss.

In an unguarded moment, a camera caught a few NATO allies joking about Trump’s long press conferences, which prompted the president to call Canadian Prime Minister Trudeau “two faced.” This week's summit has been somewhat bumpy, but is the 70 year old NATO alliance still on track? Christiane speaks with President Trump’s Ambassador to NATO, Kay Bailey Hutchison.

Emmy Award-winning director Feras Fayyad's film "The Cave" documents the work of Syrian doctor Amani Ballour as she manages an underground hospital in Ghouta, outside Damascus. Hari Sreenivasan sits down with Fayyad to discuss the film and his own traumatic experience of being kidnapped and imprisoned in Syria. Their conversation contains images of war victims and descriptions of torture.

Some of President Macron's sharpest criticisms today were aimed at President Erdogan, while Erdogan has called Macron "brain dead" for questioning his offensive into Syria, and is now blocking a NATO defense plan for the Baltics and Poland unless Turkey receives support for its effort to defeat Syrian Kurd forces on its borders. Erdogan's senior advisor joins Christiane to discuss the situation.

President Trump is in London for NATO's 70th's birthday, proud that other members are contributing more money to the defense organization than before. But there was also tension on display today between Trump and French President Macron, as they sparred over NATO, ISIS and Turkey. Bobby Ghosh, a veteran analyst of foreign affairs, joins the program to assess the fallout.

A new exhibition of female Iranian artists curated by photographer and filmmaker Shirin Neshat explores the nexus between politics, protest and culture. Christiane speaks with Neshat alongside another prominent Iranian exile, human rights activist Hadi Ghaemi, to discuss the history and emotional significance behind the exhibition.

Today, digital companies are confronted with the question of how to protect free speech while enforcing appropriate standards and practices. Jonah Peretti is co-founder of The Huffington Post and the CEO of BuzzFeed—two of the most recognizable brands on the internet—and he says our media ecosystem is broken. Peretti speaks with Walter about what "public interest" means in this online age.

President Trump is on his way to London for this week's NATO leaders' meeting. He has famously called the organization obsolete, while recently French President Macron called NATO "brain dead." Jens Stoltenberg is the NATO Secretary General facing an unenviable task trying to keep squabbling nations united, and he sits down with Christiane to preview this anniversary summit.

For French and U.S. perspectives on the NATO summit, Christiane speaks with former French Ambassador to the U.S. Gérard Araud, as well as former U.S. State Department adviser Karin von Hippel.

Nearly 25 years after the assassination of Israeli Prime Minister Yitzhak Rabin, a new film is reexamining that traumatic event. "Incitement" looks at the assassination from the perspective of Rabin's killer, a religious Jewish extremist, and the film's co-writer and director joins the show to discuss why he felt a need to tell this story now.

In “From Generosity to Justice: A New Gospel of Wealth”, Darren Walker articulates a bold vision for philanthropy in the 21st century, joined by an array of thinkers, activists, and leaders from every field, sector, and walk of life. Walker sits down with Walter Isaacson to discuss his personal journey and how philanthropy can be a tool for achieving economic, social, and political justice.

Britain’s chief rabbi has publicly rebuked Jeremy Corbyn and his party for their handling of antisemitism within its ranks. Corbyn staunchly denies he is antisemitic, but in a recent interview, he refused four times to apologize to the Jewish community. Julia Neuberger is a member of the House of Lords, a senior rabbi, and the author of “Antisemitism: What It Is. What It Isn’t. Why It Matters.”

Ahead of World AIDS Day, 130 people with HIV/AIDS from around the world have created a collaborative storytelling project entitled “Through Positive Eyes." Academic and activist David Gere heads the project and his brother, actor Richard Gere, wrote the forward to the accompanying book. They join the show to discuss their activism and how they’ve been personally affected by losing friends to AIDS.

After a flurry of campaigning in Virginia and Arizona, former New York City Mayor Michael Bloomberg will pause for Thanksgiving – but only briefly. He’s got some catching up to do in the race for the Democratic nomination, after officially declaring he’s running on Sunday. His campaign manager sits down with Christiane to explain why the billionaire businessman has jumped into the race now.