As evidence mounts in the murder of Saudi journalist Jamal Khashoggi, could the international backlash end the war in Yemen? At least 10,000 people have died there and millions more face imminent famine. David Beasley, Executive Director of the World Food Programme, just returned from Yemen and is now lobbying European leaders to help stem the suffering.

Award-winning Yemeni human rights activist Radhya Almutawakel joins the program, as she meets with members of Congress in Washington to raise awareness around the millions of lives in jeopardy in Yemen.

December marks 20 years since President Bill Clinton’s impeachment. Now, the investigation that trawled the President’s personal life is the subject of a six-part docuseries, “The Clinton Affair,” and features the most extensive conversation to date with one of its central characters: Monica Lewinsky. Series director Blair Foster joins the program to discuss that historic period in U.S. politics.

Alicia Menendez sits down with comedian Mike Birbiglia to discuss his new one-man show on Broadway, “The New One.”

Jeff Goldblum’s acting career already has a cult following. Now he sits down with Christiane Amanpour to discuss a brand-new endeavour: his debut jazz album.

Christiane Amanpour sits down with Syrian-American doctor Rim Al-Bezem to discuss her highly unusual, personal foreign policy intervention, as she and her friends managed to lobby their elected leaders, including President Trump.

2020 speculation is in full swing and Sen. Kirsten Gillibrand looks like a serious contender. She joins the program to discuss the Democrats’ prospects, as well as her timely children’s book, “Bold and Brave: Ten Heroes Who Won Women the Right to Vote.”

Walter Isaacson sits down with Ben Jaffe, to discuss a new documentary “A Tuba to Cuba,” exploring the legacy of his family, known as saviours of New Orleans jazz, and why he believes diversity is at the core of the genre.

As the President keeps up his verbal assault on the Mueller investigation, award-winning author and national security expert Tim Weiner joins the program to discuss who will protect the rule of law.

As government ministers resign in Britain over their Prime Minister’s Brexit plan, former Head of the Foreign Office Simon Fraser joins the program to weigh-in on the country’s state of turmoil.

Hari Sreenivasan sits down with entrepreneur Casey Gerald to discuss his new memoir “There Will Be No Miracles Here” and his amazing life story.

Paul Simon is a musical shapeshifter whose career spans decades. He’s now releasing a new album “In the Blue Light” and sat down with Christiane Amanpour on the heels of a global farewell tour, to discuss his life, work and new music.

Roger Ailes reshaped American media and politics by founding Fox News. Christiane Amanpour talks to Alexis Bloom, the director of the new documentary “Divide and Conquer: The Story of Roger Ailes,” as well as Alisyn Camerota, an anchor who worked closely with Ailes at Fox News.

As we come to grips with the dangers of digital media, Walter Isaacson speaks with Jennifer Pahlka, a tech innovator and founder of Code for America, who argues technology is still a force for good.

As Iran calls newly re-imposed U.S. sanctions “an act of economic war,” the Iranian Ambassador to the UK, Hamid Baeidinejad, joins the program.

Abbi Jacobson, one of Comedy Central’s biggest stars, joins the program to discuss her hit comedy “Broad City” as well as a new memoir reflecting on love, loss and work.

As California residents face an unprecedented disaster, in an exclusive interview, Christiane Amanpour speaks to Gov. Jerry Brown about the worst fires in California history.

In the US, 20 states have filed a lawsuit to repeal pre-existing condition protection from the Affordable Care Act. New York Times bestselling author and journalist Kurt Eichenwald joins the program to discuss what it’s like to navigate the country’s healthcare system with epilepsy, and the struggles he has faced with discrimination, medical incompetence, and sexual abuse.

On her first day in the job, the new head of Planned Parenthood Dr. Leana Wen joins the program to discuss what the organization means to her and its role in a country where healthcare is at the center of political debate.

In the wake of high-profile mass shootings in the US, some doctors are calling for a public health approach to tackle gun violence. Dr. Judy Melinek joins the program to discuss the role of doctors in the gun debate, tensions between some doctors and the NRA, and the #ThisISMyLane and #ThisISOurLane movements.