Comedian Colin Quinn thinks the state of the union is so far gone that America needs to break up, with his latest show exploring both sides of the political divide. He speaks with Hari Sreenivasan to discuss how to be funny in today’s era of political correctness, and why he thinks compromise doesn’t work.

Historian Deborah Lipstadt has spent her life ensuring the Holocaust is not forgotten. She famously defeated Holocaust denier David Irving in a libel suit in British High Court and is Professor of Modern Jewish History and Holocaust Studies at Emory University. She joins Walter Isaacson to discuss how we can fight the scourge of antisemitism and hate.

Greta Thunberg is a 16-year-old climate activist who has taken the world by storm speaking out to convince policy-makers to take action on issues related to climate change. She joins Christiane Amanpour to discuss her activism.

Hilde Schramm is the daughter of Nazi Minister of Armaments and War Production Albert Speer who has spent her life helping Germany atone for its sins. In honor of Holocaust Remembrance Day, she joins Christiane Amanpour to talk about her incredible life story.

Following the longest government shutdown in US history, the showdown between President Trump and Congress ended without any money for his border wall. As many credit House Speaker Nancy Pelosi’s negotiating skills, former Vice President of the Trump Organization Barbara Res and former Republican Congresswoman Mia Love join the program to break down this tussle at the top.

Member of the Venezuelan National Assembly Francisco Sucre discusses his support of Nicolás Maduro’s challenger, Assembly President Juan Guaido, and his efforts to convince the EU to formally recognize Guaido as the interim Venezuelan President.

As the U.S. recognizes Venezuela’s interim President and imposes sanctions on the country’s state oil company, Senator Bob Menendez joins the program to discuss possible repercussions, including a violent crackdown by Nicolás Maduro.

General Stanley McChrystal and author Sean McFate discuss the changing face of war, and why the world order America and its allies have fought hard to protect is now on shaky ground.

Plácido Domingo is the world’s most successful opera singer. Christiane Amanpour met him behind-the-scenes as he prepared for his sold-out show in London.

Alicia Menendez sits down with renowned African-American feminist and sociology professor Tressie McMillan Cottom to discuss her new book, "Thick: And Other Essays."

The Washington Post's Jason Rezaian recounts in chilling detail what it was like to be imprisoned on trumped-up charges in Tehran's Evin prison for 544 days.

Top German cabinet minister Jens Span joins the program to discuss rocky relations between the US and Germany as their two leaders suffer through a strained relationship.

Colombian President, Iván Duque, discusses why, along with the US, his country is also supporting the power grab in the neighboring country of Venezuela.

Walter Isaacson sits down with Native American writer David Treuer, to discuss his new memoir and why he believes America is at war with itself.

The political crisis in Venezuela has taken a dramatic turn as the leader of the opposition declares himself interim President. Democratic Congressman Adam Schiff discusses why, despite a government crisis of its own, the US was the leading country to announce its approval, as well as developments around the Russia investigation and President Trump's former lawyer, Michael Cohen.

Hari Sreenivasan sits down with Sarah El Deeb, Syria correspondent for the Associated Press, to discuss the many conflicts on the ground there, and the human toll of a country cut into pieces.