Former Commander of Allied Troops in Afghanistan Stanley McChrystal joins the program to discuss whether America is losing its longest war.

Former Mexican Foreign Minister Jorge Castañeda says that if the people marching want to claim asylum in the United States, they should be allowed to pass through Mexico. He joins to discuss.

Hollywood power couple James and Suzy Amis Cameron are fighting climate change, one meal at a time. They join the program to discuss how that one meal can change the planet.

Alicia Menendez speaks with comedian and writer Phoebe Robinson about her new book, "Everything's Trash, But It's Okay."

Should Saudi Arabia’s botched handling of the Jamal Khashoggi killing threaten the Kingdom’s status as a regional power? Former CIA Director and Secretary of Defense Robert Gates joins the program to discuss.

Jahana Hayes could become Connecticut’s first black democrat in Congress. She shares her remarkable journey with Michel Martin.

As condemnation of Saudi Crown Prince Mohammed Bin Salman continues, the International Rescue Committee’s Sanj Srikanthan joins the program to look at what’s called the Crown Prince’s war in Yemen, which is backed by the United States.

Pulitzer Prize-winning journalist Fox Butterfield joins the program to discuss his new book, which explores whether crime is something passed down through families.

As President Trump gets debriefed on the latest from Saudi Arabia, fallout grows over the disappearance of journalist Jamal Khashoggi. New York Times Columnist Thomas Friedman tells Christiane Amanpour about his struggle to square his early support for the Crown Prince with Mohammed Bin Salman’s authoritarian streak.

Alicia Menendez sits down with Amandla Stenberg, star of the new movie “The Hate U Give.”

Former San Antonio Mayor Julian Castro has the resume and the personal story to help leap democrats out of the doldrums. But does his party have a “Latino problem?”

Cindy Shank was imprisoned for fifteen years for her boyfriend’s crimes. She and her brother, filmmaker Rudy Valdez, talk to Hari Sreenivasan about the compulsory sentence that tore their family apart.

As evidence mounts tying the disappearance of Saudi journalist Jamal Khashoggi to the country’s Crown Prince, will Republican Senators stand up for a moral American policy? Senator Ben Sasse joins the program to discuss. His new book wrestles with the anger kicked up by America’s deeply divided political scene.

Two other guests weigh-in: prominent Saudi dissident, scholar Madawi Al-Rasheed says she now feels threatened by the long arm of the regime, and Taha Ozhan was an adviser to the former Turkish Prime Minister and considered Khashoggi a friend.

Biochemist Jennifer Doudna tells Walter Isaacson about the extraordinary gene-editing technology, CRISPR.

The disappearance of Saudi journalist Jamal Khashoggi puts the spotlight on reporters who put their lives on the line. Celebrated correspondent Marie Colvin gave her life in Syria, and now the Hollywood actress Rosamund Pike plays her in a new film. She joins the program along with Colvin’s friend and fellow journalist Lindsey Hilsum, who has written a new biography about her life.

No sign yet of any public explanation as sources say the Kingdom is preparing to admit Jamal Khashoggi’s death was the result of a botched interrogation. CNN International Diplomatic Editor Nic Robertson joins the program from Istanbul.

Shocking reports of voter suppression ahead of the U.S. midterms. Carol Anderson, author of “One Person, No Vote,” joins the program to discuss how the rules and technicalities of voting are becoming a partisan tactic to weigh down the opposition, threatening our democracy.

Actor Paul Dano tries his hand at directing, to great reviews. Dano and his lead actress Carey Mulligan join the program to discuss the new film “Wildlife.”