Brett McGurk, former US Special Envoy for the Global Coalition to Counter ISIS, has worked across three administrations. He joins the program to discuss his shock resignation and how the President's Syria policy could galvanize ISIS instead of beating it.

Author Reniqua Allen spoke to dozens of black millennials from all over the US for her new book, "It Was All a Dream: A New Generation Confronts the Broken Promise to Black America." She joins the program to discuss why so many young black Americans feel disillusioned today.

Whether it’s the US government shutdown or the UK’s Brexit chaos, best-selling author of “Winners Take All” Anand Giridharadas explains why he thinks society’s global elites are to blame.

Alicia Menendez sits down with #ShoutYourAbortion co-founder Lindy West to discuss her blog confronting sexual assault, her memoir and why so many women’s issues are still considered taboo.

Danish actor Mads Mikkelsen has featured in blockbuster hits, from Casino Royale to Doctor Strange. Now he joins the program to discuss his new survival movie “Arctic.”

Walter Isaacson sits down with Tim Wu, author of “The Curse of Bigness” to discuss how we’ve abandoned anti-trust and economic regulation laws to the public’s detriment.

R. Kelly is responsible for some of the 90s most enduring hits. But the six-part Lifetime series “Surviving R. Kelly” explores allegations of sexual misconduct, including sexual abuse of minors, that have surrounded the R&B star for two decades, charges he’s always denied. Tarana Burke, founder of the "Me Too" Movement, joins the program to discuss the prevalent culture of sexual assault.

As the government shutdown jeopardizes the US economy and continues in the midst of crisis overseas, Republican congressman and a veteran of the wars in Iraq and Afghanistan joins the program to discuss.

As the British Prime Minister Theresa May faces a no confidence vote in her government, just over 70 days to go before Brexit is supposed to happen, Defense Minister Tobias Ellwood joins the program to discuss the dysfunction in his country’s government, and the nation’s future.

First Vice President of the European Commission Frans Timmermans tells Christiane Amanpour that after a year and a half of negotiations, the European Union has done its part, and it’s now Britain’s responsibility to figure out just what it wants to do.

Renowned actor Richard E. Grant, star of the cult classic “Withnail and I,” joins the program to discuss a new role in “Can You Ever Forgive Me” as well his poignant childhood.

Michel Martin sits down with Ellie Kemper, star of “Unbreakable Kimmy Schmidt,” to discuss her new memoir, “My Squirrel Days.”

For decades, America – and the world – have worshiped at the feet of Silicon Valley and its mega-profitable innovations. But Scott Galloway says that these giants have rolled the dice, passed go, and collected the world, using what he terms “Jedi mind tricks” to convince us of a dubious reality.

Ilhan Omar made history to become the first Somali-American legislator in the US, and – along with Michigan’s Rashida Tlaib – the first Muslim woman in Congress. She spoke with Christiane Amanpour about Steve King’s “white supremacist” remarks, the government shutdown, her own historic position, and her efforts to enact a so-called “Green New Deal”.

A black baby born in America is more than twice as likely to die as an infant than a white baby – a disparity that’s even wider than it was in 1850. Why is this happening, and how can it be changed? Journalist Linda Villarosa joins the program to discuss.

Alicia Menendez sits down with Kairos Founder & CEO Ankur Jain to discuss why millennials are one of our best assets in tackling social issues.

Celebrated actress Jamie Lee Curtis discusses her new role in political thriller “An Acceptable Loss,” as well as how she battled opioid addiction and won.

As bombshell reports on investigations into President Trump’s relationship with Russia surface, former chair of the US House Intelligence Committee Mike Rogers joins the program.

Michel Martin sits down with Alex Long & Monique Brown, two of the subjects of the documentary film “Charm City” which focuses on issues of police-community relations in Baltimore.

Mark Munoz is a Fire Captain with the U.S. Forest Service and has been on furlough since the U.S. Government shut down on December 22, 2019. He joins Christiane Amanpour to talk about the far-reaching and personal effects of the shutdown.