Maryam Mirzakhani was the first woman, as well as the first Iranian, to be awarded a Fields Medal, the highest honor in mathematics, in 2014. Mirzakhani, who died at 40 from breast cancer in 2017, is the focus of a new biopic, "Secrets of the Surface." Her lifelong friend, math professor Roya Beheshti, speaks with Christiane about Mirzakhani’s legacy and her beautiful mind.

Israel heads to the polls yet again on Tuesday for its fourth election in two years. For the first time in Israeli history, polls are indicating that the Labor Party might be completely shut out in the election. This is the uphill battle facing the current leader, Merav Michaeli, who is also the only woman leading a major party into this election. She joins the show to discuss the issues at stake.

A new poll shows Brazilian President Bolsonaro’s popularity at a record low after he ridiculed the pandemic, scorned lockdowns, and repeatedly attacked Brazil’s democratic institutions. Now his most formidable opponent, former President Lula da Silva, has joined the fray. Lula speaks with Christiane in a world exclusive interview, his first since his corruption conviction was overturned.

Residents in Jackson, Mississippi, spent a month without water, unable to wash, flush or drink, after the February winter storm turned the taps dry and forced a citywide “boil water” advisory. Today, restrictions finally were lifted and most of the city’s water system has been restored. But is the crisis really over? The city's mayor Chokwe Antar Lumumba joins the show to discuss.

Pro basketball player Jeremy Lin is best known for generating the craze “Linsanity” after he unexpectedly led a winning turnaround with the New York Knicks in 2012. Just before Tuesday's deadly attack in Atlanta, Lin spoke with Michel Martin about racism in sports and why he's choosing to speak out.

John Hume Jr. and Martin Luther King III join the program to reflect on the peace movement and their fathers' legacies.

The Biden administration faces the largest surge of migrants the U.S. has seen in 20 years, with border patrol apprehending nearly 100,000 asylum seekers in February, including around 10,000 unaccompanied minors. Elizabeth Neumann leads the Council on National Security and Immigration, which is making the case for bipartisan reform on this issue.

Doctors and scientists say there is no evidence of any link between the AstraZeneca vaccine and blood clots, while the head of the European Medicines Agency said today the benefits of the vaccine far outweigh the risk. To discuss our tendency to rush to cause-and-effect thinking, Christiane speaks with former WHO official Anthony Costello and renowned British statistician David Spiegelhalter.

A startling new report finds one in three women globally is subjected to physical or sexual abuse in their lifetime. To discuss this and the need for male allies in the campaign against misogyny and abuse, Christiane speaks with Mandu Reid, leader of the UK Women’s Equality Party, alongside Jackson Katz, an anti-sexism educator and co-founder of Mentors In Violence Prevention.

More than a fifth of Americans have now received at least one COVID-19 vaccine shot, with over two million people vaccinated each day. But getting all those shots into all those arms is a massive logistical challenge, and now Salesforce is using its vast computing resources to help health agencies around the world track vaccinations. CEO Marc Benioff discusses this endeavor with Hari Sreenivasan.

Brazilian President Jair Bolsonaro is facing total calamity, with the country's death toll at over 275,000 and nearly all ICUs at peak capacity. Luiz Henrique Mandetta was Brazil's health minister until he was fired by Bolsonaro at the height of the country's first wave. He joins the show from Sao Paulo to discuss how it all went so wrong, and where Brazil goes from here.

10 years ago today, the war in Syria erupted and calamity followed. As the world stood by and watched, the country faced a brutal crackdown under Bashar Al-Assad, a flourishing of extreme Islamic terrorists across the region, and foreign powers entering the fight to prop up Syria’s dictator. Filmmakers Waad Al-Kateab and Gianfranco Rosi join the program to reflect on the past decade of turmoil.

Starting Monday, President Biden will travel the nation in the wake of signing into law a historic sweeping relief package. It amounts to almost $2 trillion in the form of direct payments, investments in public health, schools, and pensions – and some estimate it could slash America’s poverty rate by a third and halve the number of poor children.

Alexander McLean is an attorney and founder of Justice Defenders, a group which aims to provide legal training for inmates and guards in multiple different countries so that they can defend themselves within often unequal justice systems. He joins the show to explain their incredible results, alongside Jane Manyonge, currently an inmate in a Kenyan prison for women and now a trained paralegal.

The film "The Father" is racking up nominations this awards season. Adapted from the international hit play, the film pulls off the feat of bringing the audience inside the head of its aging protagonist, played by Anthony Hopkins, as dementia strips away his ability to process the world around him. Writer and director Florian Zeller joins the program to discuss his inspiration.

A unanimous UN Security Council statement has been issued condemning the violence – a notable diplomatic achievement by Ambassador Barbara Woodward, who ensured China, Russia, India and Vietnam were all on board. What more can the international community do to stop the violence and restore democracy to Myanmar? Ambassador Woodward joins the program to discuss.