Tom Mueller – no relation to Bob – is a New York Times bestselling author who has spent years studying the complex relationship between whistleblowers and society. His new book is a timely reminder of the challenges and the personal cost to those who dare to tell the truth, and he sits down with Michel to explain how this is ultimately about upholding American values.

U.S. Secretary of Defense Mark Esper is in Saudi Arabia today, amid the deployment of thousands of new U.S. troops to the country to try and visibly confront Iran. Meanwhile, the tumultuous withdrawal of U.S. forces from Syria looks set to benefit Iran’s regional ambitions, as well as Russia’s and the Syrian regime’s. Esper joins Christiane for an exclusive interview in Saudi Arabia.

Rhiannon Giddens is a folk singer and multi-instrumentalist who also happens to be a classically trained opera singer. Having grown up in North Carolina, she’s now on a mission to re-frame the history of African Americans and their contributions to the musical landscape. Giddens sits down with Walter to discuss her latest album, “There Is No Other,” and play a little banjo.

Christiane sits down with Peter Frankopan and Malte Herwig to discuss Peter Handke's controversial Nobel Prize Win. WARNING: This segment contains graphic images.

Grayson Perry is a London-based contemporary sculptor, carpet weaver, print-maker and ceramicist. His work challenges the fashions and foibles of the world’s collector class, while his public experiments in gender identity challenge our own innate prejudices. His latest exhibition is typically sly, with the barbed title of “Super Rich Interior Decoration.” Christiane joins him in the gallery.

Gulalai Ismail has been an advocate for human rights in Pakistan since she was 16 years old. For years, she has spoken out about abuses against women and girls, and last year, she began to advocate for victims of alleged sexual assault by Pakistan’s army – and for that, she has paid a very big price. She sits down with Michel Martin to discuss her experiences.

In testimony to the Congressional impeachment inquiry, the U.S. Ambassador to the EU Gordon Sondland says that President Trump directed him to work through Rudy Giuliani rather than government channels. It’s the latest development in the impeachment saga, much of which has focused on conflicting claims of corruption. Ukraine and disinformation expert Nina Jankowicz joins the program to discuss.

The UK and the EU have announced a Brexit deal – again. Prime Minister Boris Johnson’s attempt to renegotiate Theresa May’s deal defied the odds and found success, but it still needs approval from the European and UK Parliaments, with the latter being a particularly difficult hurdle to clear. Jonathan Powell joins the program to weigh in on the situation.

After a contentious meeting at the White House, House Leader Nancy Pelosi says she warned President Trump that, “the Russians have been trying to get a foothold in the Middle East for a very long time, unsuccessfully, and now the president has given them the opportunity" by pulling troops out of Northern Syria. Mikhail Kasyanov joins the program to explain Putin's role in this situation.

Deepak Chopra is a bestselling author, New Age wellness guru and integrative medicine advocate. He became famous for teaching household names such as Oprah and Madonna how to meditate. His books have been translated into dozens of languages and his 89th book is "Metahuman: Unleashing Your Infinite Potential." He sits down with Hari to discuss the state of the world.

Since the General Manger of leading NBA franchise, the Houston Rockets, tweeted support for Hong Kong protesters, the political fallout has been huge. The NBA swiftly responded that the statement was "regrettable" and that the organization has "great respect for the history and culture of China." Charles Barkley, a 16 season veteran of the NBA, joins Christiane to give his take on the controversy.

With another Democratic debate last night, voters got to see a different side of the candidates. Held in the midst of an impeachment inquiry and the renewed outbreak of war and humanitarian catastrophe in Syria, voters finally got a better idea of each candidate’s foreign policy and how they fare under the spotlight. Activist Brittany Packnett and columnist Medhi Hasan break down what they saw.

One of the premier songwriters of the Rock and Roll era, Hall of Fame legend Robbie Robertson is best known as the lead guitarist and chief songwriter for The Band. He joins Walter to discuss his new solo album "Sinematic," his work with Martin Scorsese in writing the music score for the film "The Irishman," and a brilliant new documentary on The Band called "Once Were Brothers."

In 2003, Katharine Gun exposed a plot by U.S. security officials to spy on United Nations members as they ramped up pressure to secure a resolution to go to war with Iraq, and she leaked the classified memo to The Observer newspaper. Now her story has been adapted into the film "Official Secrets" starring Keira Knightley. Gun sits down with Christiane to share her story.

Jack Goldsmith, the former head of the office of legal counsel under former President George W. Bush, joins Christiane Amanpour to discuss the whistle blower inquiry and the limits of executive power.

Raj Chetty believes he may have found a way to reignite the American Dream. Using "Big Data," Chetty says we can offer equality of opportunity to kids of disadvantaged backgrounds. The renowned Harvard Professor has received plaudits for his work in harnessing data to propose solutions to economic inequality. He sits down with Hari to explain his work.

Jane Fonda has moved to Washington D.C. to launch "Fire Drill Fridays," where each week she will spearhead climate protests outside of Capitol Hill. Partly inspired by Swedish teenager Greta Thunberg’s activism, Jane lit up social media after being arrested during her first climate protest on Friday. She discusses her activism with Christiane.

Over the weekend, the situation in Northern Syria became drastic with the United Nations reporting more than 150,000 people displaced by the Turkish offensive. A U.S. withdrawal from the region has left a clear political and security vacuum. Shiraz Maher and Kori Schake join Christiane for an in-depth discussion about the continuing crisis.

There are few people who have been involved in as many critical decisions as Susan Rice. Serving in numerous capacities in both the Clinton and Obama administrations, Rice has helped to significantly shape U.S. foreign policy over the past two decades. She sits down with Walter Isaacson to discuss her new memoir, "Tough Love," which reflects on her career and legacy.

It has been twelve months since the brutal murder of Washington Post journalist and vocal critic of the Saudi regime, Jamal Khashoggi, at a Saudi Embassy in Turkey. A new book by award-winning journalist Jonathan Rugman offers a fresh insight into both the methodical planning and brutal execution of Khashoggi. He joins Christiane to discuss these revelations.