Patton Oswalt may be best known for his roles in sitcoms like “The King of Queens” and voicing beloved animated characters – including a rodent with a culinary flair in “Ratatouille”. But he has faced adversity in his personal life, which he confronts in his new stand-up show “Annihilation”, touring the UK and US this summer. Oswalt spoke with Hari about his career and healing grief with laughter.

Michel Martin sits down with the host of HBO’s “Problem Areas,” which explores the nation’s most pressing issues through a satirical lens, and why this season they’re focusing on inequality in education.

David Kwong is a man of many tricks – a New York Times crossword constructor and a magician, he’s known for his particularly cerebral type of magic. His sold-out show “The Enigmatist” is an immersive evening of puzzles and illusions at the High Line Hotel in New York City, and he sat down with Walter Isaacson to discuss it.

Hari Sreenivasan sits down with Stacey Cunningham, who has well and truly smashed the glass ceiling over Wall Street. Stepping onto the trading floor as an intern in the 90s, she’s now taken the helm of the New York Stock Exchange, becoming the first female president in the organization’s 200 plus year history.

German Chancellor Angela Merkel has been called the de facto leader of Europe. Voters this weekend turned out in record numbers to push the Green Party to great success in Germany, while the far right and the center ground both fell short. In the wake of that result, Merkel grants an extremely rare and exclusive interview to Christiane in Berlin.

As a director, Ron Howard has created huge commercial and critical hits, with films like Apollo 13, A Beautiful Mind, and Rush. His new documentary looks at the life and work of opera’s legendary divo Luciano Pavarotti, and he speaks with Christiane about the singer and much more from New York.

Hari Sreenivasan sits down with Mark Bertolini, the former CEO of Aetna, to discuss the state of healthcare in America and how events in his personal life shaped his own understanding of patient care.

Hari Sreenivasan sits down with 2020 presidential candidate Andrew Yang, to discuss why the former tech executive believes he can stand-out in a crowded democratic field.

Christiane Amanpour speaks to David Miliband, former British foreign secretary and now President & CEO of the International Rescue Committee, to discuss how Ebola has returned to strike again in the Democratic Republic of the Congo, where more than a thousand people are already dead.

As Prime Minister Theresa May announces she will resign her post, former Swedish Prime Minister Carl Bildt and editor of The Spectator Fraser Nelson join the program to discuss a legacy marked by disunion in May’s party and country, as well as what this means for Britain’s exit from the European Union.

Michel Martin sits down with Eric Liu, a former Clinton administration advisor and CEO of the non-profit “Citizen University,” to discuss the lessons in civility he argues for in his book, “Become America: Civic Sermons on Love, Responsibility, and Democracy.”

Walter Isaacson sits down with restaurant critic Ruth Reichl to discuss her new memoir, “Save Me the Plums,” and her life-long passion for food.

Hari Sreenivasan speaks to Prof. Suketu Mehta, author of “This is Our Land,” who argues the West is being destroyed not by immigrants, but the fear of immigrants.

Alicia Menendez speaks to author of “All That You Leave Behind,” Erin Lee Carr. Her father was star journalist David Carr, who collapsed in the New York Times newsroom in 2015. She discusses her father’s legacy and her own grief.

Hari Sreenivasan sits down with Rachel Lears, director of “Knock Down the House,” to discuss the year she spent documenting the highs and lows of campaigning against the establishment, by following would-be freshmen in the 2018 midterm elections, including one Alexandria Ocasio-Cortez.

Hatice Cengiz was engaged to Washington Post journalist Jamal Khashoggi, who was brutally murdered inside the Saudi consulate in Istanbul. She joins the program seven months later to discuss the lack of justice for him and how she’s working tirelessly to make sure those responsible for his murder are held accountable.

Christiane Amanpour speaks to the editor-in-chief of Vanity Fair, Radhika Jones, about her first year heading the influential magazine, why she’s put diversity front and center, and what Vanity Fair’s role will be in the 2020 race.

While President Trump ran for office promising to put America first and avoid foreign wars, America is in the midst of a brutal trade war with China and is now edging closer towards armed conflict with Iran. The New Yorker’s Robin Wright joins the program to discuss the troubling state of U.S. foreign diplomacy.

Hari Sreenivasan sits down with Raj Kumar, author of “The Business of Changing the World,” to discuss the Trump administration’s immigration plans and the humanitarian crisis developing on the United States’ southern border.

Alicia Menendez sits down with Oscar-winning musician and actor Common, about his new memoir “Let Love Have the Last Word,” in which he documents his struggle to become a better father, and the strength it took to reveal his own childhood abuse.