Is all that we know about the laws of the universe about to change? Physicists are over the moon about the discovery that a subatomic particle is behaving in a way nobody could have predicted. It means that there may be a new theory of nature out there, yet to be discovered. It’s a complicated matter, but for theoretical physicist Michio Kaku, it is truly thrilling. He joins Walter Isaacson.

How will rising tensions between Israel and Iran impact ongoing talks to revive the Iran Nuclear Deal? Senator Chris Coons is a close confidant of President Biden with an eye on foreign policy, having recently returned from a trip to Ethiopia. He joins the program from Capitol Hill.

What is going on between Israel and Iran, and what is the endgame? To explain what is happening and where it could lead, Christiane speaks with reporter Ronen Bergman.

In 1991, 15-year-old Latasha Harlins was killed by an LA convenience store owner who falsely accused her of stealing. Her death and the beating of Rodney King by the LAPD prompted the devastating LA riots in 1992. A newly released, Oscar-nominated documentary shines a light on the life of a young girl whose promise went unfulfilled. The film's director, Sophia Nahli Allison, joins the show.

Automation, an increasingly dominant force in all of our lives, is the subject to which journalist Kevin Roose turns his attention in his new book "Futureproof." The book looks at how to navigate a future dominated by algorithms and AI -- and how not to be replaced by a machine at work. Roose speaks with Hari Sreenivasan about ways we can peacefully coexist with machines.

"The Trial of the Chicago 7" is a riveting courtroom drama with a host of acclaimed actors – including the man behind Borat, Sacha Baron Cohen. Christiane spoke with Baron Cohen alongside “Chicago 7” writer/director Aaron Sorkin to discuss the resonance of that trial today, the Capitol Hill insurrection, and the very real danger in making the Borat sequel.

Tom Vilsack, U.S. Secretary of Agriculture for eight years, was the Obama Administration's longest-serving cabinet member. Now Vilsack has returned to head the Department of Agriculture for the Biden administration. He joins Walter Isaacson to discuss the assistance the department has provided to farmers throughout the pandemic, as well as his plans for reform.

While countries like the UK and the U.S. are moving quickly towards vaccine-backed herd immunity, too many other countries are nowhere near this goal. Former Prime Minister Gordon Brown joins the program to discuss global mass vaccination -- which he believes must receive highest priority -- as well as the life and death of Prince Philip.

Prince Philip passed away peacefully this morning just two months shy of his 100th birthday. In a statement, Buckingham Palace spoke of the Queen's "deep sorrow" at losing her beloved husband of more than 70 years. Simon Lewis joins Christiane to reflect on Philip's legacy in the monarchy. Lewis served as communications secretary to the Queen from 1998 through 2000.

In Vienna, momentum is building on the vital effort to revive the 2015 Iran nuclear deal. The United States and Iran are still not talking directly, and plenty of sticking points remain. For insight into the Iranians' position on the issues, Christiane spoke with Iran's Foreign Ministry Spokesman, Saeed Khatibzadeh.

Prince Philip was just 26 when he married then-Crown Princess Elizabeth -- in full pomp and pageantry -- in 1947. No one could have foreseen that the union would last some 73 years -- outlasting wars, scandals and countless global challenges to the monarchy. To reflect on the past 70 years, Christiane speaks with legendary historians Margaret MacMillan.

Like the Queen, Prince Philip was deeply committed to the commonwealth. Leaders of those nations have been paying tribute to the Duke including Australian Prime Minister Scott Morrison who said, "the commonwealth family joins together in sorrow and thanksgiving for the loss and life of Prince Philip." The Secretary-General of the Commonwealth of Nations reflects on the Duke's impact.

Dorothy A. Brown is a law professor and nationally recognized scholar in tax policy. She chose her field because she believed it was free from racism. She soon discovered how wrong she was. Her new book, "The Whiteness of Wealth: How the Tax System Impoverishes Black Americans and How We Can Fix It," draws on decades of research and personal histories, as she explains to Michel Martin.

The film "One Night in Miami…" is a fictional reimagining of an historic night. In 1964, Malcolm X, Sam Cooke and Jim Brown gathered in a Miami hotel room to celebrate the world heavyweight victory of Cassius Clay, soon to be known as Muhammad Ali. The film is the feature directorial debut of Oscar-winning actor Regina King. She joins the show alongside screenwriter Kemp Powers.

For many, the outcome of the trial of Derek Chauvin is a litmus test for racial justice and policing in America. Christiane discusses the stakes with former police chief Donald De Lucca and former federal prosecutor Laura Coates.

Phillip Atiba Goff is one of the country's leading scholars on law enforcement and race. Tracie Keesee is a former police captain with the Denver Police Department. They join Michel to explain how the Center for Policing Equity is working to strengthen the relationship between police and the communities they serve.

To reach the border, migrants must make long and arduous journeys from their home countries. VICE news correspondent Paola Ramos headed down to Colombia's border with Panama and joined migrants as they trekked through the dangerous jungles known as the Darién Gap. She spoke with Christiane about the experience.

Palestine is gearing up for its first election in fifteen years. Its outcome will have a major impact on U.S. policy and the elusive Israel-Palestine peace deal. Former Palestinian Foreign Minister Nasser al-Kidwa has formed a new independent party and is running in May's elections. He joins Christiane to discuss his platform.

Now, a musical odyssey to one of the most remote places on earth. Mahani Teave's love for classical music began as a child when the first piano arrived on Rapa Nui, or "Easter Island," as it was named by the first European explorer to arrive in 1772. But then she gave it all up to create the first music school at home. Mahani Teave joins Christiane from Rapa Nui to tell her fascinating story.

Health inequality was badly exposed during this pandemic, [but Priti Krishtel says it doesn't have to be this way. She is the Co-Founder and Executive Director of the non-profit Initiative for Medicines, Access & Knowledge. She spoke to Hari Sreenivasan about the need to rethink how patents are regulated.